Pharmacogenomics: DNA Guided Prescribing in 72 Hours

Trial?and?Error Prescribing Ends Here

Adverse drug reactions (ADRs) hospitalise more than one million Americans annually and cost the system $30?billion. Devansh Lab Werks 38?genePharmacogenomics (PGx) Panel transforms a cheek swab into lifelong prescribing guidance, aligning medications with the patients genetic blueprint.

1?Inside the 38?Gene Panel

2.?Workflow: Swab to Report

1. Physician e?orders kit in DLW portal.
2. Patient swabs cheeks at home; prepaid mailer returns sample.
3. Next?generation sequencing ??500 depth.
4. Pharmacist verifies CPIC?aligned recommendations.
5. PDF report + 15?minute tele?pharmacogenomics consult delivered in 72hours.

3.?Evidence Snapshot

A 2024 JAMA Psychiatry meta?analysis (21 RCTs, 5,800 patients) showed a 36?percent higher remission rate for PGx?guided antidepressant therapy. DLWs internal study of 350 patients mirrored the benefit72?percent remission vs 51?percent under standard care. Cardiologists cite TRITON?TIMI38: CYP2C19 loss?of?function doubled stent?thrombosis risk on clopidogrel.

4.?MythsBusted

Myth: PGx is experimental.
Fact: CPIC and Dutch guidelines cover over 140 gene?drug pairs.

Myth: Insurers wont pay.
Fact: Medicare and 29state BCBS plans reimburse PGx linked to covered drugs.

5?Case Story: Faster Relief from Depression

Emma, 34 tried three SSRIs without success. DLWs report flagged her a CYP2D6 poor metaboliser. Switching to sertraline at half the standard dose dropped her PHQ?9 score from 18 to 6 in eight weeks and ended her two?year medication carousel.

Final Takeaway

Stop guessing prescriptions. Put DNA inside every eRx with DLWs Pharmacogenomics Panel.